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体温胶囊经口腔摄入进入体内,通过胃、肠道,由肛门排出。胶囊自身具有记忆功能,测量对象无需佩戴任何监测器而进行无限制的测量。使用简单方便,用于多个科研领域。金年会还有动物的核心体温胶囊。
外部温度和环境湿度会将与物理力有关的热应力放大,人体体温调节机制的饱和系统性地导致性能下降,并可迅速导致体温过高。基于可摄取电子胶囊的e-Celsius Performance®解决方案可实现对核心体温的连续监测。系统能够识别和传输温度,并连续记录人体的核*心温度,在1米范围之内都可以收集到可靠的实验数据。
在运行项目的应用中:很多项目都具备测试条件,特别是有氧运动为主的项目,如自行车,长跑,铁人三项;也可应用于橄榄球和跳水项目。
多种规格可供选择,有专门的人体型号,也有多种用于实验室大鼠、小鼠、比格犬等动物的型号。
体温胶囊的主要特点:
· 体积小巧,食用方便,对机体无损害;
· 实时、连续、无创监测;
· 无线无导管测量,测试对象亦无需实时佩戴监测器,实现无限制测量方案;
· 胶囊内置存储记忆功能,可存储多达2000组数据,无需担心数据丢失;
· 监测器可同时监测3枚胶囊数据,且自身可多达7台并联,实现高通量测量;
主要技术参数:
· 人用体温胶囊,经口服摄入,通过消化道排泄,体内时间1-2天(因人而异)
· 测量参数:测量温度范围25-45℃,精确度0.02℃,采样频率30Hz(可设定),内部可存储2000组数据;
· 传输参数:传输距离1m,传输频率433Hz;
· 规格参数:17.7*8.9mm,重1.7g,可存储时间1年,开始使用后20天;
· 可同时监测并显示3枚胶囊传输数据,并可通过PC/MAC观察分析;
· 每台监测器可存储80000组数据;
主要应用领域:
· 体温过低/高温中暑预防:体温测量降低低温/高温恶劣环境损害,或加强对发热、寒战等的感知;
· 运动热身/恢复监测:监测人体锻炼各阶段体温的变化,有助于判断机体运动技能;
· 技能评估、优化:用于评估机体体温调节或心脏节律调节功能等;
· 量化、预防、规避时差影响:监测体温昼夜节律变化,制定合理作息,从而规避时差影响等;
· 睡眠、昼夜节律和运动表现分析:通过体温变化反映机体睡眠、昼夜节律、运动等规律。
参考文献:
1. Michael Douglas Reed et al., (2019)“IL-17a promotes sociability in mouse models of neurodevelopmental disorders” Nature doi:10.1038/s41586-019-1843-6
2. Topilko T et al.,(2022) “ Edinger-Westphal peptidergic neurons enable maternal preparatory nesting” Neuron doi:10.1016/j.neuron.2022.01.012
3. NPJ Vaccines et al., (2022) “Safety and immunogenicity of four-segmented Rift Valley fever virus in the common marmoset” NPJ Vaccines DOI:10.1038/s41541-022-00476-y
4. Laperrousaz et al., (2018) “Lipoprotein Lipase Expression in Hypothalamus is involved in the Central Regulation of Thermogenesis and the Response to Cold Exposure” Frontiers in Endocrinology doi: 10.3389/fendo.2018.00103
5. Meyer et al., (2017) “Body Temperature Measurements for Metabolic Phenotyping in Mice” Frontiers in Endocrinology doi: 10.3389/fendo.2018.00103
6. Rufiange et al., (2020) “Pre-warming before general anesthesia with isoflurane delays the onset of hypothermia in rats” PLoS One doi: 10.1371/journal.pone.0219722
7. Tattersall et al., (2016) “Novel energy-saving strategies to multiple stressors in birds: the ultradian regulation of body temperature” P Roy Soc B-Biol Sci doi: 10.1098/rspb.2022.0526
8. Schulze et al., (2018) “Body temperature of bitches in the first week after parturition measured by ingestible loggers” Reproduction in Domestic Animals doi:10.1111/rda.13330
9. Guisle et al., (2020) “Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature” Sleep doi:10.1093/sleep/zsz266
10. Thi Cuc Mai et al.,(2021) “Low-Level Radiofrequency Exposure Induces Vasoconstriction in Rats.” Sci Rep DOI:10.1002/bem.22350
eCelsius
11. Mart Toots et al., (2019) “Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia Sci Transl Med ”doi:10.1016/j.xcrm.2021.100408
12. van Maanen L et al., (2019) “Core body temperature speeds up temporal processing and choice behavior under deadlines” Sci Rep doi:10.1038/s41598-019-46073-3
13. Marine Alhammoud et al.,(2021)“Thermoregulation and shivering responses in elite alpine skiers” Eur J Sport Sci doi:10.1080/17461391.2020.1754470
14. Christopher J. Stevens et al.,(2018) “Effect of two-weeks endurance training wearing additional clothing in a temperate outdoor environment on performance and physiology in the heat ” Temperature (Austin) doi:10.1080/23328940.2018.1474672
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